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Literature summary extracted from

  • Stolz, F.; Reiner, M.; Blume, A.; Reutter, W.; Schmidt, R.R.
    Novel UDP-glycal derivatives as transition state analogue inhibitors of UDP-GlcNAc 2-epimerase (2004), J. Org. Chem., 69, 665-679.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.1.3.14 3-acetamido-2,6-anhydro-3-deoxy-D-arabino-hept-2-enopyranosonate
-
 Rattus norvegicus
5.1.3.14 uridine 5'-(3-acetamido-3-deoxy-2-O-methyl-alpha-D-gluco-hept-2-ulopyranos-1-yl diphosphate)
-
 Rattus norvegicus
5.1.3.14 uridine 5'-(3-acetamido-3-deoxy-2-O-methyl-alpha-D-manno-hept-2-ulopyranos-1-yl diphosphate) weak Rattus norvegicus
5.1.3.14 uridine 5'-[(Z)-2,6-anhydro-1-deoxy-D-galactohept-1-enitol-1-yl phosphono] phosphate weak Rattus norvegicus
5.1.3.14 uridine 5'-[(Z)-2,6-anhydro-1-deoxy-D-glucohept-1-enitol-1-yl phosphono] phosphate
-
 Rattus norvegicus
5.1.3.14 uridine 5'-[(Z)-2,6-anhydro-1-deoxy-D-mannohept-1-enitol-1-yl phosphono] phosphate
-
 Rattus norvegicus
5.1.3.14 uridine 5'-[(Z)-3-acetamido-2,6-anhydro-1,3-dideoxy-D-arabino-hept-1-enitol-1-yl phosphono] phosphate
-
 Rattus norvegicus
5.1.3.14 uridine 5'-[(Z)-3-acetamido-2,6-anhydro-1,3-dideoxy-D-gluco-hept-1-enitol-1-yl phosphono] phosphate
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.1.3.14 additional information Rattus norvegicus the enzyme catalyzes the first step of sialic acid biosynthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.1.3.14 Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.1.3.14 additional information the enzyme catalyzes the first step of sialic acid biosynthesis Rattus norvegicus ?
-
 ?